MIR6859-1

Across TCGA pan-cancer cohorts, MIR6859-1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR6859-1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR6859-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6859-1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

KIRC, PAAD, and UVM are the cancer types where MIR6859-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.502	0.720	<.001	78	view →
PAAD	DFS	Quartile	All	0.562	0.345	.002	43	view →
UVM	DFS	Median	III,IV	0.324	0.769	<.001	43	view →
UCS	DFS	Median	III,IV	0.570	0.272	.011	36	view →
BLCA	OS	Quartile	II,III,IV	0.775	0.635	.004	34	view →
ACC	OS	Quartile	II,III,IV	0.352	0.663	.009	31	view →
UCEC	OS	Quartile	IV	0.873	0.149	.001	24	view →
PRAD	DFS	Median	All	0.691	0.844	<.001	22	view →
LGG	DFS	Median	All	0.785	0.880	<.001	22	view →
LUSC	OS	Median	III,IV	0.676	0.332	<.001	21	view →
THCA	DFS	Quartile	II,III,IV	0.748	0.873	.019	20	view →
BRCA	OS	Median	II,III,IV	0.645	0.487	.006	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR6859-1–KIRC (DFS)

Open the KIRC breakdown →