MIR6859-1

Across TCGA pan-cancer cohorts, MIR6859-1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR6859-1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MIR6859-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR6859-1 is over-expressed in tumor.

COAD, KIRC, and HNSC are the cancer types where MIR6859-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR6859-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.888	<.001	8	view →
KIRC	All	All	+0.303	.002	6	view →
HNSC	Female	II,III,IV	+0.609	.003	4	view →
CHOL	All	All	+1.353	.001	3	view →
LIHC	All	All	+0.232	.007	3	view →
READ	Female	All	+1.832	.008	2	view →
BLCA	All	All	+0.636	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MIR6859-1–COAD

Open the COAD breakdown →