MIR6780B

Across TCGA pan-cancer cohorts, MIR6780B RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MIR6780B data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher MIR6780B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6780B expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.

TGCT, LUSC, and UCEC are the cancer types where MIR6780B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	II,III,IV	0.339	0.955	<.001	66	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
UCEC	OS	Tertile	IV	0.225	0.772	<.001	36	view →
ESCA	OS	Quartile	III,IV	0.670	0.329	.027	18	view →
OV	OS	Tertile	IV	0.738	0.313	.001	12	view →
CHOL	OS	Tertile	All	0.154	0.793	.004	9	view →
BLCA	DFS	Tertile	IV	0.246	0.488	.035	9	view →
ACC	DFS	Tertile	All	1.000	0.417	.025	9	view →
LGG	DFS	Tertile	All	0.767	0.843	.029	9	view →
LIHC	DFS	Tertile	III,IV	1.000	0.284	.016	9	view →
LUAD	OS	Tertile	All	0.916	0.813	.032	6	view →
PAAD	DFS	Tertile	All	0.643	0.461	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MIR6780B–TGCT (DFS)

Open the TGCT breakdown →