MIR6080

Across TCGA patient cohorts, MIR6080 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6080-associated genes across cancer lineages are SNORD114-7, RNU6-642P, and RNU6-1331P. Each is linked with MIR6080 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6080-to-partner and partner-to-MIR6080 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-7 grouped by MIR6080-low versus MIR6080-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6080→partner) and Y-score (partner→MIR6080) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD114-7 →	+0.347	+4.555	.001	.005	3	1
UCEC	RNU6-642P →	+0.426	+3.827	<.001	.003	3	1
UCEC	RNU6-1331P →	+0.409	+3.666	.001	.004	3	1
UCEC	KRTAP20-3 →	+0.177	+5.738	<.001	<.001	3	1
UCEC	RNA5SP247 →	+0.879	+4.264	<.001	<.001	3	1
UCEC	PPIAP17 →	+0.189	+3.579	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

SNORD114-7 by MIR6080 expression — UCEC

Explore this box plot interactively →