Across TCGA pan-cancer cohorts, MIR580 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR580 data layer.
The strongest signal is observed in cholangiocarcinoma (CHOL), where higher MIR580 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR580 expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.
CHOL, DLBC, and THYM are the cancer types where MIR580 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.