Across TCGA pan-cancer cohorts, MIR580 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR580’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR580 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR580 is over-expressed in tumor.
LUSC, LUAD, and KICH are the cancer types where MIR580 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR580 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.