MIR548I2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR548I2 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR548I2-associated genes across cancer lineages are SPATA31D3, LINC00474, and VENTXP2. Each is linked with MIR548I2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR548I2-to-partner and partner-to-MIR548I2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR548I2→partner) and Y-score (partner→MIR548I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSPATA31D3 →+0.009+7.924<.001<.00131
LUADLINC00474 →+0.165+5.410<.001.00531
LUADVENTXP2 →+0.877+5.217<.001.00731
LUADHSFY4P →+0.038+6.584<.001.00131
LUADMTCYBP42 →+0.051+6.444<.001.00131
LUADRAD23BP2 →+0.036+5.554<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

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