MIR518A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR518A1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR518A1-associated genes across cancer lineages are MIR6864, IGKV1OR-2, and OR5I1. Each is linked with MIR518A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR518A1-to-partner and partner-to-MIR518A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR518A1→partner) and Y-score (partner→MIR518A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6864 →+0.840+4.061.003.00231
UCECIGKV1OR-2 →+0.400+3.393<.001.00731
UCECOR5I1 →+0.045+4.226<.001.00831
BRCAMIR3646 →+0.269+7.731<.001.00931
LUADOR11H1 →+0.024+7.930<.001.00831
LUADOR5L2 →+0.034+7.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration