Q-omics provides the consensus-scored MIR3646 profile across patient tissues and cancer cell-line models. MIR3646 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, MIR3646 is differentially expressed in 6, with the highest sampling consensus in KICH. Additionally, MIR3646 RNA expression shows 12,282 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight MESO, KICH, and TGCT as cancer lineages where MIR3646 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR3646 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR3646 survival associations across molecular data types. MIR3646 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR3646 RNA expression–survival associations across cancer types. High MIR3646 expression shows unfavorable associations in MESO, HNSC, ESCA and SKCM, but favorable associations in READ and KIRP. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for MIR3646 RNA expression.
This table summarizes MIR3646 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MIR3646. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR3646 shows lower tumor expression in KICH, COAD and CHOL and higher tumor expression in STAD, LIHC and KIRC. The KICH box plot shows higher MIR3646 RNA expression in normal versus tumor tissue (log2 FC = −1.115, t-test p < 0.001).
This table shows molecular features associated with MIR3646 in patient tissues and cancer cell lines. In patient samples, MIR3646 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
