MIR514B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR514B mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR514B-associated genes across cancer lineages are MIR3133, MIR4736, and MIR3181. Each is linked with MIR514B in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR514B-to-partner and partner-to-MIR514B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3133 grouped by MIR514B-low versus MIR514B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR514B→partner) and Y-score (partner→MIR514B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR3133 →+0.536+5.133.002.00831
UCECMIR4736 →+0.730+7.049<.001<.00131
UCECMIR3181 →+0.520+6.335<.001.00131
UCECIGKV2OR2-7D →+0.182+5.771<.001.00331
UCECRNU6-668P →+0.433+5.771.002.00331
UCECRNU6-662P →+0.555+5.299.003.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MIR3133 by MIR514B expression — UCEC

Box plot of MIR3133 in MIR514B-low vs MIR514B-high samples in UCEC.

Explore this box plot interactively →

Exploration