MIR514B

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR514B RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MIR514B data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR514B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR514B expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.

KIRC, LUAD, and BRCA are the cancer types where MIR514B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianAll0.7110.550<.001158view →
LUADDFSTertileIII,IV0.0360.673<.00163view →
BRCAOSTertileAll0.1360.578.01336view →
HNSCOSTertileIII,IV0.1470.687<.00136view →
COADOSTertileAll0.9250.743.00631view →
LIHCDFSTertileII,III,IV0.4750.200.0419view →
KIRPDFSQuartileAll1.0000.646.0278view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MIR514B–KIRC (DFS)

Kaplan–Meier survival curve for MIR514B RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration