Q-omics provides the consensus-scored MIR3181 profile across patient tissues and cancer cell-line models. MIR3181 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, MIR3181 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, MIR3181 RNA expression shows 8,979 significant gene co-expression associations, with the highest sampling consensus in PCPG. Together, these results highlight THCA, HNSC, and PCPG as cancer lineages where MIR3181 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR3181 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR3181 survival associations across molecular data types. MIR3181 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR3181 RNA expression–survival associations across cancer types. High MIR3181 expression shows unfavorable associations in THCA, CHOL, TGCT, MESO, ACC and LUSC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify THCA as the clearest survival context for MIR3181 RNA expression.
This table summarizes MIR3181 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR3181. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR3181 shows lower tumor expression in ESCA and STAD and higher tumor expression in HNSC and KIRC. The HNSC box plot shows higher MIR3181 RNA expression in tumor versus normal tissue (log2 FC = +0.236, t-test p = .005).
This table shows molecular features associated with MIR3181 in patient tissues and cancer cell lines. In patient samples, MIR3181 shows the broadest associations at the RNA and protein expression levels, with PCPG recurring as the lineage with the largest associated feature set.
