Across TCGA patient cohorts, MIR508 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MIR508-associated genes across cancer lineages are RNU6-349P, RBMY1KP, and MIR6823. Each is linked with MIR508 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR508-to-partner and partner-to-MIR508 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR508→partner) and Y-score (partner→MIR508) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-349P →	+0.497	+7.741	<.001	.009	3	1
COAD	RBMY1KP →	+0.144	+7.741	<.001	.009	3	1
COAD	MIR6823 →	+0.723	+7.741	<.001	.009	3	1
LUAD	RNU6-361P →	+0.463	+7.930	<.001	.008	3	1
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	1
LUAD	RNU6-365P →	+0.270	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

MIR508 survival (RNA) · tumor vs normal (RNA) · all MIR508 data types