Q-omics provides the consensus-scored MIR498 profile across patient tissues and cancer cell-line models. MIR498 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, MIR498 RNA expression shows 13,178 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight BRCA, and COAD as cancer lineages where MIR498 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR498 survival associations across molecular data types. MIR498 RNA expression shows survival associations in the most cancer types (6), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR498 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	BRCA (138)	view →
Mutation	Kaplan–Meier	2	ESCA (12)	view →

This table ranks reproducible MIR498 RNA expression–survival associations across cancer types. High MIR498 expression shows unfavorable associations in BRCA, HNSC, ESCA, LUAD and SKCM, but favorable associations in STAD. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for MIR498 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.562	0.924	<.001	138	view →
HNSC	OS	Tertile	III,IV	0.001	0.675	<.001	42	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LUAD	OS	Tertile	All	0.275	0.685	.006	36	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	18	view →
STAD	OS	Quartile	IV	0.661	0.272	.033	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

MIR498-BRCA (OS)

Kaplan–Meier survival curve for MIR498 RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR498 in patient tissues and cancer cell lines. In patient samples, MIR498 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	13,178	COAD (4411)	view →
Function (RNA)	6,434	STAD (5928)	view →
▼Mutation
RNA	8	SKCM (8)	view →