Across TCGA patient cohorts, MIR498 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR498-associated genes across cancer lineages are MIR6827, NIFKP7, and MIR4769. Each is linked with MIR498 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR498-to-partner and partner-to-MIR498 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR498→partner) and Y-score (partner→MIR498) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6827 →	+0.614	+5.362	<.001	.005	3	1
SKCM	NIFKP7 →	+0.060	+5.159	<.001	.007	3	1
SKCM	MIR4769 →	+0.700	+6.199	<.001	.001	3	1
SKCM	OR1E3 →	+0.058	+6.328	<.001	.001	3	1
SKCM	RNVU1-18 →	+0.276	+5.159	<.001	.007	3	1
SKCM	RNA5SP492 →	+0.503	+5.037	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

MIR498 survival (RNA) · tumor vs normal (RNA) · all MIR498 data types