Across TCGA patient cohorts, MIR498 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,434 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR498-associated GO terms across cancer lineages are Protein folding, Cardiocyte differentiation, and Obsolete calcium-mediated signaling using intracellular calcium source. Each is linked with MIR498 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR498-to-partner and partner-to-MIR498 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR498→partner) and Y-score (partner→MIR498) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein folding →	+0.124	+0.172	<.001	<.001	3	8
ESCA	Cardiocyte differentiation →	+0.079	+0.148	<.001	.001	3	7
STAD	Obsolete calcium-mediated signaling using intracellular calcium source →	+0.063	+0.183	<.001	<.001	3	7
ESCA	Myoblast differentiation →	+0.113	+0.249	<.001	.001	3	7
STAD	Negative regulation of Notch signaling pathway →	+0.084	+0.245	<.001	<.001	3	7
ESCA	Organelle fusion →	+0.102	+0.187	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,434 associations by consensus.

Exploration

MIR498 survival (RNA) · tumor vs normal (RNA) · all MIR498 data types