MIR4754

Across TCGA patient cohorts, MIR4754 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,857 significant associations in total. OV shows the largest number of these associations.

The most reproducible MIR4754-associated GO terms across cancer lineages are Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, Protein histidyl modification to diphthamide, and Mitochondrial cytochrome c oxidase assembly. Each is linked with MIR4754 in more than 13 cancer types. Because this analysis shows association rather than direction, both MIR4754-to-partner and partner-to-MIR4754 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence grouped by MIR4754-low versus MIR4754-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4754→partner) and Y-score (partner→MIR4754) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.050	+0.834	<.001	<.001	2	14
KIRP	Protein histidyl modification to diphthamide →	+0.026	+0.332	<.001	<.001	3	13
ACC	Mitochondrial cytochrome c oxidase assembly →	+0.030	+0.557	<.001	<.001	3	13
LAML	Smoothened signaling pathway →	+0.024	+0.870	<.001	<.001	3	12
STAD	Protein-containing complex localization →	+0.024	+0.235	.003	.004	3	12
OV	Positive regulation of DNA repair →	+0.013	+0.329	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,857 associations by consensus.

Protein insertion into ER membrane by stop-transfer membrane-anchor sequence by MIR4754 expression — THYM

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