MIR4754

Across TCGA pan-cancer cohorts, MIR4754 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4754’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR4754 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4754 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where MIR4754 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4754 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.224	.008	4	view →
COAD	Female	All	+0.859	.004	3	view →
KIRP	Female	II,III,IV	+0.664	.008	2	view →
THCA	Female	All	−0.388	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4754–KIRC

Open the KIRC breakdown →