MIR4754

Across TCGA pan-cancer cohorts, MIR4754 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MIR4754 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MIR4754 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4754 expression acts as an unfavorable survival marker, although some lineages such as KIRP and STAD show a favorable association.

THCA, KIRP, and STAD are the cancer types where MIR4754 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	All	0.787	0.950	<.001	60	view →
KIRP	OS	Tertile	All	1.000	0.612	.003	47	view →
STAD	OS	Tertile	All	0.545	0.337	<.001	43	view →
LGG	OS	Tertile	All	0.352	0.505	<.001	35	view →
LUAD	DFS	Median	IV	0.212	0.777	.001	34	view →
PRAD	DFS	Quartile	All	0.753	0.915	.003	20	view →
PAAD	OS	Tertile	All	0.569	0.288	.002	16	view →
SKCM	OS	Median	All	0.839	0.901	.006	15	view →
COAD	OS	Quartile	All	0.423	0.730	.009	13	view →
BLCA	DFS	Median	IV	0.281	0.605	.003	9	view →
MESO	OS	Quartile	IV	0.756	0.295	.026	9	view →
LIHC	OS	Median	II,III,IV	0.680	0.349	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MIR4754–THCA (DFS)

Open the THCA breakdown →