MIR4740

Across TCGA patient cohorts, MIR4740 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR4740-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Methylglyoxal metabolic process, and Peptidyl-arginine methylation. Each is linked with MIR4740 in more than 16 cancer types. Because this analysis shows association rather than direction, both MIR4740-to-partner and partner-to-MIR4740 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by MIR4740-low versus MIR4740-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4740→partner) and Y-score (partner→MIR4740) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.041	+0.629	<.001	<.001	3	17
LUAD	Methylglyoxal metabolic process →	+0.042	+0.740	<.001	<.001	3	16
UVM	Peptidyl-arginine methylation →	+0.042	+0.709	<.001	.004	2	17
KIRC	Negative regulation of protein K63-linked ubiquitination →	+0.042	+0.759	<.001	<.001	3	16
KIRC	Protein deacetylation →	+0.032	+0.825	<.001	<.001	3	16
THYM	Depyrimidination →	+0.049	+1.430	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by MIR4740 expression — GBM

Explore this box plot interactively →