Q-omics provides the consensus-scored MIR4740 profile across patient tissues and cancer cell-line models. MIR4740 expression is associated with patient survival in 30 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR4740 is differentially expressed in 11, with the highest sampling consensus in KICH. Additionally, MIR4740 RNA expression shows 14,275 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UVM, KICH, and THYM as cancer lineages where MIR4740 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4740 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4740 survival associations across molecular data types. MIR4740 RNA expression shows survival associations in the most cancer types (30). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4740 RNA expression–survival associations across cancer types. High MIR4740 expression shows unfavorable associations in UVM, LIHC, ACC and ESCA, but favorable associations in MESO and UCS. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR4740 RNA expression.
This table summarizes MIR4740 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4740. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4740 shows lower tumor expression in KICH, UCEC and BRCA and higher tumor expression in CHOL, ESCA and LIHC. The KICH box plot shows higher MIR4740 RNA expression in normal versus tumor tissue (log2 FC = −1.787, t-test p < 0.001).
This table shows molecular features associated with MIR4740 in patient tissues and cancer cell lines. In patient samples, MIR4740 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
