MIR4740

Across TCGA pan-cancer cohorts, MIR4740 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MIR4740’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MIR4740 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4740 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, UCEC, and BRCA are the cancer types where MIR4740 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4740 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.787	<.001	6	view →
UCEC	All	All	−1.270	<.001	6	view →
BRCA	All	II,III,IV	−0.823	<.001	6	view →
CHOL	Female	All	+3.686	<.001	5	view →
ESCA	Male	All	+1.636	<.001	4	view →
LIHC	Female	All	+0.985	<.001	4	view →
KIRP	Male	II,III,IV	−0.885	.029	3	view →
STAD	Male	IV	+1.250	<.001	2	view →
READ	All	All	−0.972	.027	2	view →
LUAD	Male	III,IV	−1.236	.006	1	view →
KIRC	Female	All	+0.590	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MIR4740–KICH

Open the KICH breakdown →