MIR4686

Across TCGA patient cohorts, MIR4686 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,412 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4686-associated GO terms across cancer lineages are Postsynapse organization, Regulation of polysaccharide metabolic process, and Vesicle-mediated transport in synapse. Each is linked with MIR4686 in more than 10 cancer types. Because this analysis shows association rather than direction, both MIR4686-to-partner and partner-to-MIR4686 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynapse organization grouped by MIR4686-low versus MIR4686-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4686→partner) and Y-score (partner→MIR4686) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Postsynapse organization →	+0.050	+0.054	<.001	<.001	3	11
STAD	Regulation of polysaccharide metabolic process →	+0.046	+0.153	<.001	<.001	3	9
LGG	Vesicle-mediated transport in synapse →	+0.076	+0.044	<.001	.001	3	8
LGG	Dendritic spine morphogenesis →	+0.055	+0.094	<.001	<.001	3	8
STAD	Intracellular protein transmembrane transport →	+0.075	+0.118	<.001	<.001	3	8
STAD	Regulation of double-strand break repair via nonhomologous end joining →	+0.059	+0.178	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,412 associations by consensus.

Postsynapse organization by MIR4686 expression — LGG

Explore this box plot interactively →