MIR4686

Across TCGA pan-cancer cohorts, MIR4686 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4686 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR4686 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4686 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

ACC, LUSC, and SKCM are the cancer types where MIR4686 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.010	0.667	<.001	135	view →
LUSC	OS	Tertile	All	0.634	0.783	.006	87	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	69	view →
CESC	OS	Tertile	III,IV	0.375	0.782	.003	66	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
UCEC	OS	Tertile	III,IV	0.589	0.835	.015	36	view →
READ	OS	Tertile	IV	0.555	0.893	.001	36	view →
PRAD	OS	Tertile	All	0.540	0.990	<.001	24	view →
BLCA	OS	Tertile	II,III,IV	0.737	0.404	.007	18	view →
LGG	DFS	Tertile	All	0.400	0.830	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4686–ACC (DFS)

Open the ACC breakdown →