MIR4686

Across TCGA pan-cancer cohorts, MIR4686 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR4686’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MIR4686 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4686 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.

LIHC, HNSC, and LUSC are the cancer types where MIR4686 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4686 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	−0.660	<.001	8	view →
HNSC	All	All	+0.307	.003	8	view →
LUSC	All	All	+0.064	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MIR4686–LIHC

Open the LIHC breakdown →