MIR4527HG

Across TCGA pan-cancer cohorts, MIR4527HG RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MIR4527HG data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR4527HG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4527HG expression acts as an unfavorable survival marker, although some lineages such as READ and HNSC show a favorable association.

KIRC, LIHC, and UCS are the cancer types where MIR4527HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.522	0.700	<.001	149	view →
LIHC	DFS	Tertile	All	0.237	0.556	<.001	87	view →
UCS	DFS	Tertile	II,III,IV	0.190	0.537	.001	80	view →
BLCA	OS	Tertile	All	0.624	0.745	.006	21	view →
SARC	OS	Quartile	All	0.344	0.559	<.001	21	view →
STAD	DFS	Tertile	II,III,IV	0.562	0.682	.019	19	view →
UVM	OS	Tertile	III,IV	0.220	0.811	.021	18	view →
MESO	DFS	Tertile	All	0.240	0.533	.031	18	view →
PCPG	DFS	Tertile	All	0.818	0.936	.014	15	view →
PAAD	OS	Tertile	All	0.494	0.639	.022	9	view →
COAD	OS	Tertile	II,III,IV	0.455	0.634	.032	6	view →
READ	DFS	Tertile	IV	1.000	0.484	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MIR4527HG–KIRC (OS)

Open the KIRC breakdown →