Q-omics provides the consensus-scored MIR4527HG profile across patient tissues and cancer cell-line models. MIR4527HG expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MIR4527HG is differentially expressed in 5, with the highest sampling consensus in THCA. Additionally, MIR4527HG RNA expression shows 6,761 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, THCA, and TGCT as cancer lineages where MIR4527HG shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4527HG — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4527HG survival associations across molecular data types. MIR4527HG RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4527HG RNA expression–survival associations across cancer types. High MIR4527HG expression shows unfavorable associations in KIRC, LIHC, UCS, BLCA, SARC and STAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MIR4527HG RNA expression.
This table summarizes MIR4527HG tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4527HG. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4527HG shows lower tumor expression in PRAD and LUSC and higher tumor expression in THCA, LUAD and KIRC. The THCA box plot shows higher MIR4527HG RNA expression in tumor versus normal tissue (log2 FC = +0.146, t-test p = .008).
This table shows molecular features associated with MIR4527HG in patient tissues and cancer cell lines. In patient samples, MIR4527HG shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
