MIR4527HG

Across TCGA pan-cancer cohorts, MIR4527HG RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR4527HG’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR4527HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4527HG is over-expressed in tumor, although a few such as PRAD and LUSC show the opposite, repressed pattern.

THCA, LUAD, and KIRC are the cancer types where MIR4527HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4527HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	+0.146	.008	6	view →
LUAD	All	All	+0.208	<.001	5	view →
KIRC	Male	All	+0.011	.007	4	view →
PRAD	All	All	−0.041	.001	2	view →
LUSC	Male	II,III,IV	−0.055	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR4527HG–THCA

Open the THCA breakdown →