MIR4516

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR4516 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,422 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR4516-associated proteins across cancer lineages are YES1, TRIO_S2282, and PRICKLE3_S437. Each is linked with MIR4516 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR4516-to-partner and partner-to-MIR4516 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4516 versus YES1 in UCEC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4516→partner) and Y-score (partner→MIR4516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECYES1 →+0.244+0.828<.001.00132
LSCCTRIO_S2282 →-1.009-0.675<.001.00232
LSCCPRICKLE3_S437 →-0.272-0.555.004.00532
LSCCRANBP3_T363 →+1.053+0.761.002.00732
OVPPP3CA_S469 →+0.842+1.052.003.00532
OVPTPN11_S558 →+0.539+0.448.003.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,422 associations by consensus.

MIR4516 vs YES1 — UCEC

Per-sample scatter of MIR4516 vs YES1 in UCEC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration