MIR4516

Across TCGA pan-cancer cohorts, MIR4516 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR4516 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MIR4516 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIR4516 expression acts as an unfavorable survival marker, although some lineages such as OV and BRCA show a favorable association.

OV, MESO, and ACC are the cancer types where MIR4516 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.745	0.651	.002	84	view →
MESO	OS	Tertile	II,III,IV	0.331	0.595	.001	81	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	81	view →
BRCA	OS	Tertile	III,IV	0.968	0.497	.003	63	view →
UVM	OS	Tertile	III,IV	0.037	0.809	<.001	42	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
TGCT	DFS	Tertile	II,III,IV	0.523	0.952	.006	36	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
DLBC	DFS	Tertile	All	0.367	0.859	.004	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
READ	DFS	Tertile	IV	0.082	0.619	.001	18	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR4516–OV (OS)

Open the OV breakdown →