MIR4504

Across TCGA patient cohorts, MIR4504 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,841 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4504-associated GO terms across cancer lineages are Signal transduction by p53 class mediator, Protein modification by small protein removal, and Heterochromatin organization. Each is linked with MIR4504 in more than 11 cancer types. Because this analysis shows association rather than direction, both MIR4504-to-partner and partner-to-MIR4504 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction by p53 class mediator grouped by MIR4504-low versus MIR4504-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4504→partner) and Y-score (partner→MIR4504) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Signal transduction by p53 class mediator →	+0.054	+0.546	<.001	<.001	3	12
STAD	Protein modification by small protein removal →	+0.053	+0.285	<.001	<.001	3	11
ESCA	Heterochromatin organization →	+0.052	+0.452	<.001	<.001	3	11
STAD	DNA-templated DNA replication maintenance of fidelity →	+0.058	+0.271	<.001	<.001	3	11
STAD	Microtubule polymerization →	+0.049	+0.255	<.001	<.001	3	11
ESCA	Positive regulation of DNA-templated transcription initiation →	+0.046	+0.552	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,841 associations by consensus.

Signal transduction by p53 class mediator by MIR4504 expression — ESCA

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