MIR4486

Across TCGA patient cohorts, MIR4486 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,970 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR4486-associated proteins across cancer lineages are SORBS2_S259, TNS2_S120, and PALM2AKAP2_S720. Each is linked with MIR4486 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR4486-to-partner and partner-to-MIR4486 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4486 versus SORBS2_S259 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4486→partner) and Y-score (partner→MIR4486) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SORBS2_S259 →	+0.599	+1.171	<.001	<.001	3	5
LSCC	TNS2_S120 →	+0.708	+1.408	<.001	<.001	3	5
LSCC	PALM2AKAP2_S720 →	+0.497	+0.849	<.001	<.001	3	4
LSCC	PARD3B_S710 →	+0.488	+1.158	<.001	<.001	2	5
LSCC	PGAM1_S31 →	-0.500	-0.858	<.001	.004	3	4
HNSC	SORBS2 →	+0.436	+0.953	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,970 associations by consensus.

MIR4486 vs SORBS2_S259 — PDAC

Explore this scatter interactively →