Q-omics provides the consensus-scored MIR4486 profile across patient tissues and cancer cell-line models. MIR4486 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, MIR4486 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, MIR4486 RNA expression shows 12,970 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight BLCA, THCA, and GBM as cancer lineages where MIR4486 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4486 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4486 survival associations across molecular data types. MIR4486 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4486 RNA expression–survival associations across cancer types. High MIR4486 expression shows unfavorable associations in BLCA, THCA, CHOL, KICH and KIRC. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for MIR4486 RNA expression.
This table summarizes MIR4486 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4486. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4486 shows lower tumor expression in THCA. The THCA box plot shows higher MIR4486 RNA expression in normal versus tumor tissue (log2 FC = −0.128, t-test p = .024).
This table shows molecular features associated with MIR4486 in patient tissues and cancer cell lines. In patient samples, MIR4486 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
