MIR4446

Across TCGA patient cohorts, MIR4446 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,630 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIR4446-associated proteins across cancer lineages are IMP4, PDCD11, and CARMIL2_S1246. Each is linked with MIR4446 in more than 5 cancer types. Because this analysis shows association rather than direction, both MIR4446-to-partner and partner-to-MIR4446 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4446 versus IMP4 in LSCC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4446→partner) and Y-score (partner→MIR4446) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IMP4 →	-0.369	-1.329	<.001	<.001	3	5
LSCC	PDCD11 →	-0.275	-0.868	<.001	.002	2	6
PDAC	CARMIL2_S1246 →	+0.663	+1.331	<.001	<.001	3	5
HNSC	GRAP2 →	+0.462	+1.150	<.001	<.001	3	5
HNSC	RGS10 →	+0.427	+1.737	<.001	<.001	3	4
UCEC	SLC15A2 →	+0.967	+1.378	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,630 associations by consensus.

MIR4446 vs IMP4 — LSCC

Explore this scatter interactively →