MIR4424

Across TCGA patient cohorts, MIR4424 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,262 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4424-associated GO terms across cancer lineages are DNA modification, Positive regulation of double-strand break repair, and RNA modification. Each is linked with MIR4424 in more than 14 cancer types. Because this analysis shows association rather than direction, both MIR4424-to-partner and partner-to-MIR4424 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA modification grouped by MIR4424-low versus MIR4424-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4424→partner) and Y-score (partner→MIR4424) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA modification →	+0.067	+0.398	<.001	<.001	3	15
UCEC	Positive regulation of double-strand break repair →	+0.074	+0.080	<.001	<.001	3	15
STAD	RNA modification →	+0.075	+0.312	<.001	<.001	3	15
STAD	Regulation of RNA splicing →	+0.095	+0.378	<.001	<.001	3	15
STAD	tRNA processing →	+0.077	+0.293	<.001	<.001	3	15
STAD	tRNA modification →	+0.073	+0.286	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,262 associations by consensus.

DNA modification by MIR4424 expression — STAD

Explore this box plot interactively →