Q-omics provides the consensus-scored MIR4424 profile across patient tissues and cancer cell-line models. MIR4424 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, MIR4424 is differentially expressed in 2, with the highest sampling consensus in STAD. Additionally, MIR4424 RNA expression shows 6,262 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight OV, and STAD as cancer lineages where MIR4424 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4424 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4424 survival associations across molecular data types. MIR4424 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4424 RNA expression–survival associations across cancer types. High MIR4424 expression shows unfavorable associations in OV, KIRC, MESO, PAAD and CHOL, but favorable associations in HNSC. The OV Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .011). Together, the overview and detailed table identify OV as the clearest survival context for MIR4424 RNA expression.
This table summarizes MIR4424 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4424. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4424 shows lower tumor expression in STAD and KIRP. The STAD box plot shows higher MIR4424 RNA expression in normal versus tumor tissue (log2 FC = −0.181, t-test p = .040).
This table shows molecular features associated with MIR4424 in patient tissues and cancer cell lines. In patient samples, MIR4424 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
