MIR4269

Across TCGA pan-cancer cohorts, MIR4269 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR4269 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR4269 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4269 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SARC show a favorable association.

UVM, LUSC, and KIRP are the cancer types where MIR4269 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.457	0.897	<.001	129	view →
LUSC	OS	Tertile	II,III,IV	0.158	0.447	<.001	99	view →
KIRP	OS	Tertile	II,III,IV	0.202	0.797	<.001	87	view →
DLBC	DFS	Tertile	All	0.390	0.944	<.001	63	view →
MESO	OS	Tertile	II,III,IV	0.178	0.661	<.001	30	view →
KIRC	DFS	Tertile	All	0.878	0.780	.009	27	view →
ACC	DFS	Quartile	All	0.182	0.581	.010	25	view →
SARC	DFS	Median	All	0.430	0.251	<.001	20	view →
LUAD	DFS	Tertile	II,III,IV	0.104	0.302	.031	15	view →
LGG	DFS	Tertile	All	0.887	0.796	.001	13	view →
LAML	DFS	Quartile	All	0.654	0.264	.008	12	view →
COAD	OS	Tertile	All	0.403	0.724	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR4269–UVM (OS)

Open the UVM breakdown →