Q-omics provides the consensus-scored MIR4269 profile across patient tissues and cancer cell-line models. MIR4269 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR4269 is differentially expressed in 11, with the highest sampling consensus in BLCA. Additionally, MIR4269 RNA expression shows 14,282 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UVM, BLCA, and THYM as cancer lineages where MIR4269 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4269 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4269 survival associations across molecular data types. MIR4269 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4269 RNA expression–survival associations across cancer types. High MIR4269 expression shows unfavorable associations in UVM, LUSC, KIRP, DLBC and MESO, but favorable associations in KIRC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR4269 RNA expression.
This table summarizes MIR4269 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4269. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4269 shows lower tumor expression in BLCA, COAD, HNSC, UCEC, BRCA and READ. The BLCA box plot shows higher MIR4269 RNA expression in normal versus tumor tissue (log2 FC = −1.890, t-test p < 0.001).
This table shows molecular features associated with MIR4269 in patient tissues and cancer cell lines. In patient samples, MIR4269 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
