MIR4257

Across TCGA patient cohorts, MIR4257 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,022 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR4257-associated GO terms across cancer lineages are Actin polymerization or depolymerization, Endosome to lysosome transport, and Stress-activated protein kinase signaling cascade. Each is linked with MIR4257 in more than 27 cancer types. Because this analysis shows association rather than direction, both MIR4257-to-partner and partner-to-MIR4257 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin polymerization or depolymerization grouped by MIR4257-low versus MIR4257-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4257→partner) and Y-score (partner→MIR4257) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Actin polymerization or depolymerization →	+0.050	+0.767	<.001	<.001	3	27
THYM	Endosome to lysosome transport →	+0.044	+0.434	<.001	<.001	3	27
ESCA	Stress-activated protein kinase signaling cascade →	+0.052	+0.925	<.001	<.001	3	27
ESCA	Endocytic recycling →	+0.041	+0.726	<.001	<.001	2	28
UVM	Lysosomal transport →	+0.044	+0.701	<.001	<.001	3	27
ESCA	Canonical NF-kappaB signal transduction →	+0.046	+0.697	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,022 associations by consensus.

Actin polymerization or depolymerization by MIR4257 expression — ESCA

Explore this box plot interactively →