Q-omics provides the consensus-scored MIR4257 profile across patient tissues and cancer cell-line models. MIR4257 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, MIR4257 is differentially expressed in 7, with the highest sampling consensus in KIRC. Additionally, MIR4257 RNA expression shows 14,108 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight THCA, KIRC, and UVM as cancer lineages where MIR4257 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4257 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4257 survival associations across molecular data types. MIR4257 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4257 RNA expression–survival associations across cancer types. High MIR4257 expression shows unfavorable associations in THCA, UVM, OV, LGG and BLCA, but favorable associations in MESO. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for MIR4257 RNA expression.
This table summarizes MIR4257 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4257. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4257 shows lower tumor expression in LUSC, BRCA, BLCA and UCEC and higher tumor expression in KIRC and CHOL. The KIRC box plot shows higher MIR4257 RNA expression in tumor versus normal tissue (log2 FC = +0.319, t-test p < 0.001).
This table shows molecular features associated with MIR4257 in patient tissues and cancer cell lines. In patient samples, MIR4257 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
