MIR381HG

Across TCGA patient cohorts, MIR381HG mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR381HG-associated genes across cancer lineages are KRTAP23-1, RNU6-1275P, and RN7SKP218. Each is linked with MIR381HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR381HG-to-partner and partner-to-MIR381HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP23-1 grouped by MIR381HG-low versus MIR381HG-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR381HG→partner) and Y-score (partner→MIR381HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	KRTAP23-1 →	+0.144	+5.199	<.001	.003	3	1
SKCM	RNU6-1275P →	+0.265	+4.867	<.001	.005	3	1
SKCM	RN7SKP218 →	+0.102	+4.680	<.001	.007	3	1
SKCM	ZNF32-AS3 →	+0.026	+4.695	.005	.003	3	1
SKCM	TRBV23OR9-2 →	+0.095	+4.970	.004	.005	3	1
SKCM	ASB15-AS1 →	+0.032	+4.241	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

KRTAP23-1 by MIR381HG expression — SKCM

Explore this box plot interactively →