Q-omics provides the consensus-scored ZNF32-AS3 profile across patient tissues and cancer cell-line models. ZNF32-AS3 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, ZNF32-AS3 is differentially expressed in 4, with the highest sampling consensus in COAD. Additionally, ZNF32-AS3 RNA expression shows 7,505 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight ACC, COAD, and THYM as cancer lineages where ZNF32-AS3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF32-AS3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF32-AS3 survival associations across molecular data types. ZNF32-AS3 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF32-AS3 RNA expression–survival associations across cancer types. High ZNF32-AS3 expression shows unfavorable associations in UVM and LUSC, but favorable associations in ACC, LGG, STAD and HNSC. The ACC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .003). Together, the overview and detailed table identify ACC as the clearest survival context for ZNF32-AS3 RNA expression.
This table summarizes ZNF32-AS3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF32-AS3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF32-AS3 shows lower tumor expression in LUAD and higher tumor expression in COAD, CHOL and LUSC. The COAD box plot shows higher ZNF32-AS3 RNA expression in tumor versus normal tissue (log2 FC = +0.028, t-test p = .015).
This table shows molecular features associated with ZNF32-AS3 in patient tissues and cancer cell lines. In patient samples, ZNF32-AS3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
