MIR378H

Across TCGA pan-cancer cohorts, MIR378H RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MIR378H data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR378H RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR378H expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRP show a favorable association.

HNSC, KIRP, and UCS are the cancer types where MIR378H RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.485	0.319	.005	72	view →
KIRP	DFS	Median	All	0.976	0.791	.005	47	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
UCEC	DFS	Quartile	All	0.778	0.869	.002	34	view →
LGG	DFS	Median	All	0.351	0.460	<.001	32	view →
GBM	DFS	Quartile	All	0.408	0.176	<.001	27	view →
COAD	DFS	Median	All	0.718	0.827	.010	17	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	17	view →
PAAD	DFS	Tertile	II,III,IV	0.400	0.256	.013	15	view →
CESC	OS	Median	IV	0.788	0.395	.022	12	view →
THCA	OS	Median	IV	0.597	1.000	.013	12	view →
BRCA	OS	Median	III,IV	0.948	0.856	.007	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MIR378H–HNSC (DFS)

Open the HNSC breakdown →