MIR378H

Across TCGA pan-cancer cohorts, MIR378H RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR378H’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR378H RNA is repressed in tumor relative to normal tissue. In most cancer types MIR378H is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and LIHC are the cancer types where MIR378H tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR378H RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.775	<.001	6	view →
LUSC	All	All	−0.680	<.001	5	view →
LIHC	All	All	+0.588	<.001	5	view →
BLCA	All	III,IV	+0.722	.011	4	view →
BRCA	Female	All	−0.670	<.001	4	view →
KIRC	All	All	+0.416	.001	4	view →
UCEC	All	IV	+1.495	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MIR378H–THCA

Open the THCA breakdown →