MIR3680-1

Across TCGA pan-cancer cohorts, MIR3680-1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MIR3680-1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR3680-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3680-1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and DLBC show a favorable association.

ACC, SKCM, and LUSC are the cancer types where MIR3680-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.448	0.721	.002	46	view →
SKCM	OS	Tertile	All	0.667	0.824	.002	40	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
UCEC	DFS	Tertile	All	0.361	0.668	.002	30	view →
MESO	DFS	Tertile	All	0.113	0.516	<.001	27	view →
BLCA	OS	Tertile	III,IV	0.744	0.615	.011	26	view →
CHOL	DFS	Tertile	III,IV	0.172	0.779	.024	21	view →
DLBC	DFS	Median	III,IV	1.000	0.423	.005	17	view →
THCA	OS	Tertile	III,IV	0.797	0.934	.022	15	view →
COAD	DFS	Quartile	All	0.357	0.599	.008	14	view →
KIRP	OS	Quartile	II,III,IV	0.385	0.689	.008	14	view →
STAD	DFS	Tertile	IV	0.095	0.546	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MIR3680-1–ACC (DFS)

Open the ACC breakdown →