MIR3680-1

Across TCGA pan-cancer cohorts, MIR3680-1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR3680-1’s most consistent transcriptional readouts.

The strongest signal is observed in cholangiocarcinoma (CHOL), where MIR3680-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3680-1 is over-expressed in tumor.

CHOL and BRCA are the cancer types where MIR3680-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR3680-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CHOL	All	II,III,IV	+1.805	<.001	3	view →
BRCA	All	All	+0.282	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MIR3680-1–CHOL

Open the CHOL breakdown →