Q-omics provides the consensus-scored MIR3680-1 profile across patient tissues and cancer cell-line models. MIR3680-1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MIR3680-1 is differentially expressed in 2, with the highest sampling consensus in CHOL. Additionally, MIR3680-1 RNA expression shows 11,402 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, CHOL, and UVM as cancer lineages where MIR3680-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR3680-1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR3680-1 survival associations across molecular data types. MIR3680-1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR3680-1 RNA expression–survival associations across cancer types. High MIR3680-1 expression shows unfavorable associations in ACC, SKCM, LUSC, UCEC and MESO, but favorable associations in BLCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify ACC as the clearest survival context for MIR3680-1 RNA expression.
This table summarizes MIR3680-1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in CHOL for RNA.
This table ranks reproducible tumor–normal expression differences for MIR3680-1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR3680-1 shows higher tumor expression in CHOL and BRCA. The CHOL box plot shows higher MIR3680-1 RNA expression in tumor versus normal tissue (log2 FC = +1.805, t-test p < 0.001).
This table shows molecular features associated with MIR3680-1 in patient tissues and cancer cell lines. In patient samples, MIR3680-1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
