MIR3180-4

Across TCGA patient cohorts, MIR3180-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,319 significant associations in total. OV shows the largest number of these associations.

The most reproducible MIR3180-4-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Regulation of stem cell population maintenance, and Epigenetic programming of gene expression. Each is linked with MIR3180-4 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR3180-4-to-partner and partner-to-MIR3180-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by MIR3180-4-low versus MIR3180-4-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR3180-4→partner) and Y-score (partner→MIR3180-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Positive regulation of stem cell population maintenance →	+0.025	+0.032	.001	<.001	3	4
BRCA	Regulation of stem cell population maintenance →	+0.026	+0.016	.001	<.001	3	4
COAD	Epigenetic programming of gene expression →	+0.046	+0.077	.002	<.001	3	3
COAD	Facultative heterochromatin formation →	+0.040	+0.048	.003	.001	3	3
STAD	Positive regulation of mitotic cell cycle phase transition →	+0.031	+0.334	<.001	<.001	3	3
LGG	Negative regulation of stem cell population maintenance →	+0.028	+0.024	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,319 associations by consensus.

Positive regulation of stem cell population maintenance by MIR3180-4 expression — LGG

Explore this box plot interactively →