MIR3180-4

Across TCGA pan-cancer cohorts, MIR3180-4 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated MIR3180-4 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR3180-4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR3180-4 expression acts as an unfavorable survival marker.

HNSC, UVM, and KIRC are the cancer types where MIR3180-4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.153	0.687	<.001	126	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
KIRC	OS	Tertile	All	0.296	0.640	.001	51	view →
MESO	DFS	Tertile	All	0.099	0.392	.030	27	view →
UCEC	OS	Tertile	IV	0.231	0.592	.036	18	view →
OV	OS	Quartile	III,IV	0.276	0.383	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MIR3180-4–HNSC (OS)

Open the HNSC breakdown →