MIR205HG

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR205HG mutation is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR205HG-associated genes across cancer lineages are PEDS1-UBE2V1, PUDPP1, and RNU6-944P. Each is linked with MIR205HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR205HG-to-partner and partner-to-MIR205HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEDS1-UBE2V1 grouped by MIR205HG-low versus MIR205HG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR205HG→partner) and Y-score (partner→MIR205HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPEDS1-UBE2V1 →+0.040+3.943.006.00732
COADPUDPP1 →+0.157+5.357<.001.00632
SKCMRNU6-944P →+0.417+3.177<.001.00132
SKCMRN7SKP224 →+0.074+3.224.005.00732
SKCMMIR607 →+0.261+3.594<.001.00332
SKCMLINC01511 →+0.131+2.961.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

PEDS1-UBE2V1 by MIR205HG expression — UCEC

Box plot of PEDS1-UBE2V1 in MIR205HG-low vs MIR205HG-high samples in UCEC.

Explore this box plot interactively →

Exploration